Friday, November 29, 2019

Merger Between Daimler

Recommendations The failed merger between Daimler-Benz and Chrysler suggests that the integration of large corporations requires in-depth assessment of external risks and possible conflicts within an organization. Provided that these precautions are not taken, even very efficient companies can become stagnant. On the whole, it is possible to make several recommendations on the basis of this case.Advertising We will write a custom report sample on Merger Between Daimler-Benz and Chrysler specifically for you for only $16.05 $11/page Learn More First of all, the management of merged companies should not be too optimistic about the performance and profitability of their organizations. The thing is that the integration of large corporations is a very time-consuming process because it is necessary to align different cultures, production methods, performance appraisal techniques and so forth. This issue is particular important in those cases when business admi nistrators set timelines or develop schedules. The management of DaimlerChrysler expected significant revenues within several years, but these expectations were unrealistic. The problem is that unrealistic expectations often lead to panic and hasty decisions. For example, many Chrysler executives were fired only because DaimlerChrysler did not attain the expected financial goals. Such a strategy only increased the tensions within the organization. Prior to the merger, the management of companies should pay close attention to the competitive positions of each other and the trends that emerged in a certain market. For example, Daimler-Benz was an indisputable leader of the German car-manufacturing industry. Moreover, they believed that the partnership with Chrysler would give them access to the U.S. market. Yet, Chrysler faced significant competition from Ford as well Toyota. Again, this recommendation is related to the problem of unrealistic expectations set by corporate executives w ho expected that the merger would become successful almost immediately. The executives of such companies should find ways of reconciling various organizational cultures. It should be noted that Daimler-Benz and Chrysler had different polices regarding executive compensation, work styles and decision-making within the company. These differences resulted in many conflicts between the employees of these corporations.Advertising Looking for report on business economics? Let's see if we can help you! Get your first paper with 15% OFF Learn More Their corporate executives should create a culture that appeal to the workers of a newly-created company. Under these circumstances, the HR managers of both companies should join their efforts and develop a set of policies related to compensation, evaluation of performance, and the structure of the new company. In this way, companies can avoid many potential conflicts. The managers of merged companies must ensure that different depa rtments or divisions of the organization can share resources, technologies or information. For instance, Chrysler did not receive any support from Daimler-Benz. Thus, corporate executives should eliminate the barriers that prevent different departments from cooperating with one another. These organizational policies were not developed in DaimlerChrysler. Business administrators should inform the employees about the future strategies and goals of an organization. The workers should now what is expected from them and how they are supposed to achieve these goals. The Chrysler employees never had an opportunity to interact with the management and discuss future activities of the organization. Many workers were not confident of their job security and this lack of certainty could adversely affect their performance. It should be noted that many former executives were fired because of satisfactory results and this influenced the overall morale with within the company. This is one of the rea sons why this merger was unsuccessful. The executives, who plan the merger of two organizations, should determine whether this partnership will be really a merger of equals. They have to decide which partner will play the leading role. The union of Daimler-Benz and Chrysler was described as the merger of equals, but this approach resulted in a great number of conflicts between the executives of the American and German divisions of DaimlerChrysler. At the very beginning, this issue was not properly addressed by the leaders of two corporations. Finally, business administrators should find ways of making large corporations less bureaucratic and hierarchical. In particular, they must ensure that workers can communicate with top executives of any organization.Advertising We will write a custom report sample on Merger Between Daimler-Benz and Chrysler specifically for you for only $16.05 $11/page Learn More This task is particular important for merged corpora tions like Chrysler and Daimler-Benz. This goal can be achieved by joining several departments and empowering workers. The managers of DaimlerChrysler did not do it. Conclusion On the whole, the merger of Daimler-Benz and Chrysler can be viewed as a valuable lesson for other companies that intend to merge with one another. Moreover, the recommendations put forward in this paper can be applicable to other industries, for instance, financial services sector, IT industry, manufacturing and so forth. Furthermore, the challenges described in this report are particularly relevant to large corporations that can be based in countries with legislation, work culture, language, and labor relations. In particular, this case illustrates the importance of reconciling different organizations, exchange of information between departments, and employee involvement. Furthermore, such a problem as unrealistic expectations can occur in various organizational settings. This is why the lessons of DaimlerC hrysler should be considered by the management of various organizations that are supposed to merge with one another; otherwise these companies will not attain their objectives. This report on Merger Between Daimler-Benz and Chrysler was written and submitted by user Jeram1ah to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Monday, November 25, 2019

Mitosis Versus Meiosis essays

Mitosis Versus Meiosis essays Mitosis and Meiosis are very different for many reasons. One reason being what they produce. Two being how they are produced. And three being what they both insure. Mitosis is different than Meiosis because of many things. The first thing would be that they produce different things. One thing that they produce differently would be that Mitosis produces body cells, also known as Somatic cells and Meiosis produces sex cells or Gametes. Mitosis produces only two daughter cells while meiosis produces four daughter cells. Another difference would be that Mitosis produces cells for growth and repair, while Meiosis produces cells for sexual reproduction. Mitosis and Meiosis are produced very differently. Instead of just the five main steps, Interphase, Prophase, Metaphase, Anaphase and Telophase, Meiosis has not only those but an additional Interphase (II ), Prophase (II), Metaphase (II), Anaphase (II), and Telophase (II). Mitosis is produced to make cells for growth and repair and meiosis is produced to make cells for sexual reproduction. Those are two very different things because cells that grow and repair help to keep those cells that already exist healthy and happy while the reproduction is used for making more cells. Mitosis and Meiosis both insure different things like Mitosis insures that all daughter cells are genetically identical, while Meiosis insures that it will generate genetic diversity through the crossing over and random separation of homologous pairs of chromosomes. Mitosis also has a difference in metaphase. In metaphase the chromosomes line up singly. In meiosis metaphase I the chromosomes line up as homologous pairs. The two double chromosomes are called a tetrad when they are lined up side by side, the crossing over occurs during the tetrad. Also there is a difference in the nuclear division of the two. In mitosis there is only one nuclear division while in meiosis there ...

Thursday, November 21, 2019

Just answer the fellowing questions Essay Example | Topics and Well Written Essays - 500 words

Just answer the fellowing questions - Essay Example Although most of the raw materials used by Samsung are manufactured in South Korea, the company also imports materials from other countries most notably the US. The company has a factory in Texas that manufactures semiconductors that are also used in the production of Apples’ iPhones and iPads. Once the product is assembled, it is packed and shipped to various Samsung wholesale stores. Retailers purchase the product from these stores before selling it to the consumer. On 1st December 2014, the New York Times published an article that highlighted China’s resolve to deny British MPs entry to Hon Kong. According to the article, the government of China has taken this step because of concerns over British attitude toward the ongoing protests in Hong Kong. Britain, on the other hand, feels that it has a responsibility of overseeing a democratic ruling of Hong Kong as per the provisions of the 1984 agreement between China and Britain (Perlez 1). The author of the article avoids adopting an orientalist explanation by withholding his opinion. To achieve this, the author focuses on reporting the situation with little evaluation. The author, therefore, leaves it to his readers to make a decision on whether the government of China is right to deny British MPs entry to Hong Kong. Orientalism is however evidenced by British lawmakers resolve to be allowed entry to Hong Kong. Terming the action by the Chinese government as â€Å"overtly confrontational, † Mr. Ottaway, a British lawmaker, does not seem to believe in China’s ability to handle the protests in Hong Kong (Perlez 1). Germany is one of the largest countries in Europe in terms of geographic area and population. Its neighbors include among other countries Belgium and France. While Germany’s international boundary with Belgium is relatively streamlined with little meanders, the country’s boundary with France seems to advance into Germany’s territory. One of the possible

Wednesday, November 20, 2019

Evaluating compliance of chemotherapy administration safety standards Research Paper

Evaluating compliance of chemotherapy administration safety standards of practice in anoncology day centre - Research Paper Example The Alfred Health Department of Haematology and Oncology day Care Unit observed the need to reduce the occurrence of and minimize risk of errors while increasing efficiency of services to its chemotherapy patients. With regard to this need, the day care unit decided to conduct a survey to evaluate if the practice is in compliance with ASCO/ONS Chemotherapy Administration Safety Standards. The researcher captured data by recording the responses of participants that were mostly ‘yes’ and ‘no’ together with short comments with regard to each standard. The findings were recorded, discussed and evaluated accordingly. After the survey it was discovered that the unit was in compliance with five of the eight ASCO/ONS Chemotherapy Administration Safety Standards. Owing to this, the survey came up with three recommendations that the unit must adhere to and implement them effectively in order to fully comply with chemotherapy administration safety standards The Alfred Health Department of Haematology and Oncology realized that there was need to come up with safety strategies that would result into minimizing the occurrence of and reduction of the risk of errors while increasing efficiency of service to its patients. Consequently, the Oncology department recognized that there were no accessible safety standards that could assist in assessing chemotherapy administration safety. Owing to these facts, the Hospital decided to conduct a survey using the American Society of Clinical Oncology (ASCO) and Oncology Nursing Society (ONS) standards that were formulated in 2008. These standards were created to assist in the administration of chemotherapy to adult patients in the outpatient setting. The hospital came up with various tools to audit techniques basing on ASCO/ONS standards. The main objective of this research report is evaluating

Monday, November 18, 2019

How cultural and personality differences impact on leadership in Essay

How cultural and personality differences impact on leadership in organizations - Essay Example This in turn is supposed to improve the organization's operational flexibility and thus the ability to deal with change. For the study of leadership, the above mentioned changes have led to the widespread adoption of empowerment strategies. Such an adoption is understandable: if one flattens an organization's structure, there is little choice but to empower the organisations lower-level workers with broader decision-making responsibilities. As a result, the traditional "limits to power" once designated by boundaries of hierarchy and rational authority are blurring [1]. This paper deals with the questions of leadership and how it is affected by culture and personality differences. The paper consists of three major parts, related respectively to leadership, culture and leadership, as well as personality and leadership, each chapter discussing theoretical concepts and empirical research. The New Leadership paradigm incorporated three main categories of theory - transactional leadership, transformational leadership, and culture-based leadership. ... Chapter 2: Transactional and transformational leadership The New Leadership paradigm incorporated three main categories of theory - transactional leadership, transformational leadership, and culture-based leadership. The transactional leadership theorists, including those theorists who explored the concept of leadership through the eyes of followers, explained leadership as contingent on a condition of transaction or exchange between leaders and followers. Alternatively, transformational leadership theory argues that "good" leadership is achieved through more than just tangible inducements. It suggested that leadership can be conceptually organized along a number of charismatic and situationally correlated dimensions [2]: charismatic leadership, inspirational leadership, intellectual stimulation, and individual consideration (See Table 1). The culture-based theorists viewed leadership as being culturally specific, where "good" leadership, among other things, primarily depends on whether or not a leader's style is in synchronization with hi s or her organization's culture [1]. The transformational leader has been characterized as one who articulates a vision of the future that can be shared with peers and subordinates, intellectually stimulates subordinates, and pays high attention to individual differences among people. This transformational leader was posited as a contrast to the transactional leader who exchanges rewards contingent upon a display of desired behaviours [3]. Burns considered the transformational leader to be distinct from the transactional leader, where the latter is viewed as a leader who initiates contact with subordinates in an effort to exchange something of value, such as rewards for

Saturday, November 16, 2019

Embryonic And Induced Pluripotent Stem Cells Biology Essay

Embryonic And Induced Pluripotent Stem Cells Biology Essay INTRODUCTION: Stem cells are cells which are found in almost all multicellular organisms. Stem cells was proposed by a histologist Maksimov. A in 1908. They develop into many different types of cells in the body during their early life and growth and serve as a internal repair system in many tissues. Formation of new cells can be seen when stem cells division starts these new cells can either form a stem cell or other types of cells like muscle cells,brain and red blood cells with specialized functions. Stem cells are the objects in biomedical research and are differentiated from other types of cells by two main characteristics. Firstly, Stem cells are the undifferentiated cell types they possess the capacity of both self renewable during cell division. Secondly, Potency which means they can be differntiated into differnt types of specialized cells with specific function.(Bishop et.al., 2002). Stem cells can be totipotent and pluripotent. In some organs like gut or bone marrow the st em cells divide either to replace or repair the damaged or worn out tissues while in other organ system like pancreas they divide under some specific function Totipotent stem cells can give rise to a functional organism as well as to every cell type of the body. Pluripotent stem cells are capable of giving rise to any tissue type, but not to a functioning organism. Multipotent stem cells are more differentiated and thus can give rise only to a few tissue types. For example, a specific type of multipotent stem cell called a mesenchymal stem cell can produce bone, muscle, cartilage, fat, and other connective tissues. (Pittenger et.al., 1999). They are two types of Stem cells 1) Embryonic stem cells 2) Adult stem cells also known as somatic cell or tissue specific. Embryonic stem cells are derived from the blastocysts and are pluripotent instead of totipotent because they do not have the ability to become part of the extra-embryonic membranes or the placenta while the adult cells are present in adult tissues while the stem cells found in developed tissues are the Adult stem cells and the example for this is the hematopoietic stem cells of blood which cannot give rise to the cells of a different tissue, such as nerve cells in the brain (Frankel et.al.,1999). The difference between between embryonic and adult stem cells(somatic) is their origin that is embryonic cells can differntiate into any c ell types but adult stem cells are limited and can differentiate into the cells of their own tissue by this the grown cells wont be rejected by the immune system during treatment and these cells also differ by mutation frequency (James et.al.,2002). The stem cells derived from the human embryo is known as Human embryonic stem cells and these cells are for reproductive purpose. While, in 2006 researchers have observed new type of specialized adult cells this cells are called as Induced pluripotent cells (iPSCs). Parthenogenetic stem cells are also one type of stem cells derived from activated human oocytes USES: Stem cells are useful in treating diseases like diabetis and heart diseases and many works are being done on how to use stem cells for cell based therapies in treating diseases which is also called as regenerative medicine. Stem cells have the ability to replace the damaged cells and can be used in treating heart failures. spinal injuries and parkinsons diseases for example, neural stem cells are able tp regenerate nerve tissue damaged by spinal injury. Stem cells are useful in screening toxins in substances such as pesticides and also used during development of new methods for gene therapy that may help those who are suffering from genetic illiness. They are also used in pharmaceutical industry for testing the new drugs before testing on animal and humans. Induced pluripotent cells are the adult stem cells have been genetically remodelled to an embryonic stem like to express genes and factors which maintains the properties of embryonic stem cells. EMBRYONIC AND INDUCED PLURIPOTENT STEM CELLS: Embryonic stem cells are from the earliest stages of human embryo that develop into eggs by invitro fertilization while other embryos are developed for research and extracted after five days growth. It is known that embryonic stem cells divide indefinitely so only a single embryo can form lines of cells to use for treatment.(Thomson et.al.,1998) These cells are undifferentiated but has a ability to differentiate into any cell, tissue or organ in the body. These stem cells can also become nerve, muscle cells or any other type of human cells. The process involved in formation of ES cells is the ovaries are removed and after 76hours of copulation they are treated with media containing serum overnight.The following day the inner cell mass of embryos are removed and cultured on fibroblast after few weeks colonies grew which showed pluripotent characters referred to as ES cells. Embryonic stem cells are used to treat a host of diseases, such as Parkinsons disease, spinal cord injury, and d iabetes (Martins.,1981). For research, these embryos are destroyed in the process of deriving embryonic stem cells. ES cells have got a great potential for long term therapies but the issue arises regarding safety. Transplanted ES cells have uncontrolled growth and could generate tumours which is seen in laboratory cultures by scientists and there are not sure how they behave inside the body. So, this is to be studied before proceeded in clinical trials while another issue is tissues derived from the ES cells are rejected by patients immune system after transplantation. To overcome this issue tissue rejection currently, drugs can be used which suppresses the immune system but these drugs can be infectious thus drugs without any side effects are being investigated by the researchers or alternatively adult stem cells can be used. The major issue is in process of extracting the embryonic cells the embryos have to be destroyed this is opposed by many people and raises ethical issues. Al ternatives are being investigating by combining the stem cell technology with cloning by a method called (SCNT) somatic cell nuclear transfer.(Stewart et.al.,2007). It is a method which involves insertion of the nuclei of the somatic cell into the oocyte which develops into the embryo. This embryo derives the embryonic stem cell lines which is carried out in several mammalian species but till date No ES cells have been successfully developed by this method and also requires destruction of many embryos compared to other methods. And the other issue by usig this method is therauptic human cloning would lead to reproductive human cloning which leads to maral and social danger. The use of ES cells got many ethical issues as it is derived by destroying the embryos which raises fundamental concers of human life. (Tabar et.al.,2001). Problems associated with stem cell research according to the researchers embryonic stem cells are known for the cell baesd therapies as they are more versatile than adult stem cells but the same properties of these cells make them unusual for therapy as these will migrate all over the body and produce tumours. Growing and maintaining embryonic cell lines prove that they are problematic by performing experiments in mice as some of these get mutated and unusable to the patients. To overcome this problem adult stem cells acan be used to eliminate mutation tissue incompatibility. The pharmaceutical companies could not puruse these therapies due to financial incentives ( Phimister and drazen,2004). Recent advances in stem cells have new applications possible for stem cell based technology. It is now possible to reprogram differentiated human somatic cells into pluripotent cells that are functionally equivalent to embryonic stem cells. In 2006, specialized adult cells are been reprogrammed genetically to assume a stem cell like state called as Induced pluripotent stem cells. (Fenno.et.al., 2008). The use of ES cells as an alternative to oocytes which can be reprogrammed as an Human somatic cells. This can be done by fusion of human embryonic stem cells with fibroblasts which results hybrid cells.(Cowan et.al.,2005). These cells exhibits morphology and growth proper of embryonic stem cells and also express their genes. Transplantation of induced pluripotent cells into mice resulted in tumour containing variety of tissues on injection into the blastocyst showed mouse embryonic development This shows that Induced Pluripotent stem cells can be produced from fibroblast on addition wi th defined factors like oct3/4,Sox2 and klf4(Takahashi and Yamanaka.,2006). Researchers have demonstrated a novel technique for production of IPS cells by transforming Adult Skin cells which is considered as a fast reliable and safe method, viruses were used to insert the specific genes into the adult cell would result in increased potential for adverse outcomes and also increases the chance of genetic defects thus it would affect the patient treating with stem cell therapy.(Soldner et.al.,2009) Thus, alternatively transgenes or reprogramming proteins can used for insertion to overcome the risk and after induction using protein factors or virus free factors that can be removed to induce pluripotency which develops into IPS cells that does not have any risk.(Kaji et.al.,2009) As, IPS cells also raises ethical problems related to germline alterations. However using virus free factors can overcome the problem of germline alteration. In 2010, researchers have used Induced pluripotent stem cells to treat rodents suffering with parkinsons disease and this research was successfull this is done by transplanting the induced pluripotent cell neuron into the rodents mid brain injury which is similar to Parkinsons disease in humans by this the cells became functional and showed improvement. Thus induced pluripotent cells may be useful for future disease models and cell-based therapies. Induced pluripotent stem cells offer immense potential for regenerative medicine and studies of development and diseases. Thus analysis of genomic transcriptional activity, gene activation, allele specific gene expression and DNA methylation shows that the somatic cell was reprogrammed to an embryonic state which provides a system for investigating the mechanisms. To Induce pluripotent somatic properties which are similar to ES cells properties is done by introducing active genes or derivatives of RNA or protein products into the somatic cell but this process of acquiring pluripotency is not genetically but involves Epigenomic Reprogramming. There are differences between ES and IPSC cells regarding chromatin structure and gene expressionby showing few similarities while the other reports show that there is epigenetic differences and alteration. Reprogramming of a somatic cell into pluripotent state requires complete change of Somatic cell to an ES cell like state but this is not repo rted yet. On performing genomic profiling of the DNA methylomes of both ES and Induced pluripotent cells similarities are seen but every single line shows different reprogramming variability compared to both ES cells and other Induced pluripotent stem cells. Patterns of DNA methylation are seen as epigenetic change at the tips and centromeres of the chromososmes and show differences in CG methylation and histone modifications. Thus, Induced pluripotent cells may not be suitable substitute for embryonic cells. (Lister et.al., 2011). CONCLUSION: Human embryonic stem (ES) cell research has been the best way for the cell-based therapies for a number of diseases but the issue raises with destroying the embryos to produce these cells. The use of IPS cells has less ethically problematic than the use of Embryonic cells as production Of IPS cells does not require destroying the embryos. But the use of induced pluripotent cells raises ethical concerns to somatic cell reprogramming as there is a difference seen between the ES and Ips cells and the debate over stem cell therapy is increasingly becoming irrelevant but ethical issues regarding the Embryonic stem cells would not entirely go away.So, the study of all the types of stem cells should be done as it is not known which is useful for the cell replacement therapticus.

Wednesday, November 13, 2019

Human Evolution In Africa :: essays research papers

Evolution In Africa   Ã‚  Ã‚  Ã‚  Ã‚  Humans, as we consider ourselves, evolved in Africa. Not entirely, but from early primates to our present state. Many people dispute this fact, despite astounding evidence supporting the theory, for various reasons. Showing all the genetic, paleological, and geological proof, I find it very hard indeed to contradict the evidence.   Ã‚  Ã‚  Ã‚  Ã‚  True, humans didn’t evolve entirely in Africa. As a matter of fact the first known ancestors of humans where found in North America, in the Utah Valley. These animals where nothing more than a shrew in the shadow of the dinosaurs. However, with the event that killed the dinosaurs, they where finally allowed to reproduce and spread. At this time, according to isotope dating, the world was averaging 4 times warmer than it now is. As time went on, the small mammal had spread throughout Eurasia. All of Eurasia then was covered in tropical forests. Primates evolved in what is now the Indian Subcontinent.   Ã‚  Ã‚  Ã‚  Ã‚  From their placement in India, then still lowland, primates spread throughout the world once more. Some returned to North America, only to be wiped out by rodents already living there. Others spread to Europe and the Middle East.   Ã‚  Ã‚  Ã‚  Ã‚  By this time, Africa had just split from marsupial overrun Gondwanaland. About a million years later it reached the Middle East, and primates moved in. By now the world had cooled enough that the primates in Europe had been decimated to near extinction. They also migrated south, for the Mediterranean Sea was at that time dry lowland. Now almost all of the primates left in the world were in Africa, and the only marsupial that wasn’t wiped out was the opossum. Primates and large cats now ruled, with rodents scarce, which meant that the primates had to adapt to keep from becoming lunch. In light of this, natural selection shows only those primates with larger bodies and higher intelligence survived.   Ã‚  Ã‚  Ã‚  Ã‚  The once rodent sized primates, lemurs, now only exist in Madagascar, which had separated from Africa in the early Eocene Epoch, and where there were no predators to be found. In most of Africa, however, the primates got larger. They shifted evolutionary gears to start becoming apes and hominids. The first apes to evolve, Afropithecus was very small by ape standards. They were dumb tree swingers, but it was by their appearance that we owe our existence, along with chimps, gorillas, and orangutans. These apes, despite their stupidity, were very successful and spread back to India once more.